Nebraska clinches the series with tonight's and will have a chance at a sweep when the two teams play on Sunday afternoon. The Huskers now lead the all-time series 16-11.
Texas Tech walked 10 batters on the evening and three of Nebraska's runs came on walked batters.
The Red Raiders out hit Nebraska 5-3 and suffered just its fourth loss of the season when totaling more hits than an opponent (24-4).
Texas Tech honored nine senior players and three student assistants in a pre-game ceremony. The Nebraska series marks Tech's final home series of the season.
Tonight's loss to Nebraska ensures that Tech will finish below .500 in Big 12 play for just the second time since the league's inception back in 1997. Tech finished 8-18 in 2003 and did not qualify for the Big 12 Tournament.