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1999 Results
| Day | Date | Opponent | Location | TV | Outcome/Time |
| Mon | 09/06/1999 | Arizona State | Tempe, Ariz. | Fox Sports | L, 31-13
Recap | Stats |
| Sat | 09/11/1999 | Louisiana-Lafayette | Lafayette, La. | | W, 38-17
Recap | Stats |
| Sat | 09/18/1999 | North Texas | Lubbock, Texas
(Alumni Band Day) | | L, 21-14
Recap | Stats |
| Sat | 10/02/1999 | Texas A&M | Lubbock, Texas | Fox Sports Net | W, 21-19
Recap | Stats |
| Sat | 10/09/1999 | Oklahoma State | Stillwater, Okla. | | L, 41-21
Recap | Stats |
| Sat | 10/16/1999 | Colorado | Lubbock, Texas
(Homecoming) | ABC | W, 31-10
Recap | Stats |
| Sat | 10/23/1999 | Baylor | Waco, Texas | | W, 35-7
Recap | Stats |
| Sat | 10/30/1999 | Missouri | Columbia, Mo. | | L, 34-7
Recap | Stats |
| Sat | 11/06/1999 | Iowa State | Lubbock, Texas
(Family Day) | | W, 28-16
Recap | Stats |
| Sat | 11/13/1999 | Texas | Austin, Texas | Fox Sports Net | L, 58-7
Recap | Stats |
| Sat | 11/20/1999 | Oklahoma | Lubbock, Texas | | W, 38-28
Recap | Stats |
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