| Day | Date | Opponent | Location | TV | Outcome/Time |
| Sat | 09/08/2001 | New Mexico | Lubbock, Texas | | W, 42-30
Recap | Final Stats |
| Sat | 09/22/2001 | North Texas | Irving, Texas (Texas Stadium) | | W, 42-14
Recap | Final Stats |
| Sat | 09/29/2001 | Texas | Austin, Texas | Fox Sports Net | L, 42-7
Recap | Final Stats | FANSlive GameTracker |
| Sat | 10/06/2001 | Kansas | Lubbock, Texas | | L, 34-31
Recap | Final Stats |
| Sat | 10/13/2001 | Kansas St | Lubbock, Texas | | W, 38-19
Recap | Final Stats | FANSlive GameTracker |
| Sat | 10/20/2001 | Nebraska | Lincoln, Neb. | FOX Sports Net | L, 41-31
Recap | Final Stats | Quotes | Notes | FANSlive GameTracker |
| Sat | 10/27/2001 | Baylor | Waco, Texas | | W, 63-19
Recap | Final Stats | FANSlive GameTracker |
| Sat | 11/03/2001 | Texas A&M | Lubbock, Texas | | 1:00 PM CT
Recap | Final Stats | FANSlive GameTracker |
| Sat | 11/10/2001 | Oklahoma St | Stillwater, Okla. | | W, 49-30
Recap | Final Stats | FANSlive GameTracker |
| Sat | 11/17/2001 | Oklahoma | Lubbock, Texas | ABC | L, 30-13
Recap | Final Stats | FANSlive GameTracker |
| Sat | 11/24/2001 | Stephen F. Austin | Lubbock, Texas | | W, 58-3
Recap | Final Stats |
| Sat | 12/29/2001 | Iowa | San Antonio, Texas (Sylvania Alamo Bowl) | | L, 19-16
Recap | Box Score | FANSlive GameTracker |
